| abstract |
THIS INVENTION DISCLOSES A METHOD FOR PRODUCING, ON A CONTINUOUS, MICRO AND / OR MULTI-COMPONENT NANOParticles, AS PARTICULARS OF MOLD OR CRYSTAL SOLID DISPERSIONS. THE CONTINUOUS METHOD UNDERSTANDS STEPS OF 1. PREPARING A FIRST SOLUTION UNDERSTANDING AT LEAST ONE COMPONENT AND AT LEAST ONE SOLVENT AND UNDERSTANDING AT LEAST ONE ANTI SOLVENT AT LEAST ONE COMPONENT UNDERSTANDED THE FIRST ONE REFERRED TO FIRST SOLUTION AND TO THE SECOND SOLUTION THROUGH MICROFLUIDIZATION TO PRODUCE A PRECIPITATION OR CO-PRECIPITATION SUSPENSION, 3. FEEDING THE REFERENCE SUSPENSION TO A FILTERING SYSTEM FOR A CURRENT CURRENT 4. CONCENTRATED TO A DRYER BY ATOMIZATION; 5. ATOMIZING THIS CONCENTRATE CURRENT USING AT LEAST ONE ATOMIZER; 6. DRYING THOSE CONCENTRATE CURRENT ATOMIZED FOR PARTICULARS, 7. COLLECT THE PARTICULARS. SINGLE COMPONENT PARTICULARS OR MULTI-COMPONENT PARTICLES, MOLD SOLID DISPERSION PARTICULARS, CO-CRYSTAL PARTICLES AND PHARMACEUTICAL COMPOSITIONS ARE ALSO DISCLOSED. |