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publicationDate 2008-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber PT-103528-A
titleOfInvention METHOD OF PRODUCTION OF NANOPARTICLES OF CALCIUM PHOSPHATES WITH HIGH PURITY AND RESPECTIVE USE
abstract The present invention relates to a method for the continuous production of phosphorous phosphate nanoparticles in a network mixing reactor or in a reactor with a static mixer (S), which is fed with solutions of calciton and phosphorus, a silane and , OPTIONALLY, A SOLVENT OR A DISPERSING AGENT. THE PROPOSED PROCESS ALLOWS THE CONTROL OF THE MICROMISTURE THAT IS ESSENTIAL FOR THE DEVELOPMENT OF PARTICLES OF NANOMETRIC STRUCTURE, BUT IT IS ALSO DETERMINING FOR THE PURITY, CRYSTALLINITY AND MORPHOLOGY OF THE CRYSTALS. ANOTHER DETERMINING FACTOR IS THE DISTRIBUTION SCHEME FOR REAGENTS AT THE REACTOR AND THROUGH THEREOF, CONTINUOUSLY OR ALTERNATED IN THE TIME, THAT WILL PERMIT TO PROGRAM THE PH OF THE REACTIONAL MIXTURE THROUGH THE REACTOR. THE SUSPENSION OF CALCIUM PHOSPHATE NANOPARTICLES COMING OUT OF THE REACTOR CAN BE AFTER SUBSTANTIVE STAGES OF AGING, ULTRASOUND, SEPARATION, DRYING, SINTERING AND GRINDING. SOME CALCIUM PHOSPHATES ARE CONSIDERED BIOMATERIALS BY WHICH THEY FIND VARIOUS APPLICATIONS AS FOOD ADDITIVES AND NUTRITIONAL SUPPLEMENTS, MATERIALS FOR REPLACEMENT, REPAIR AND BONE INCREASES, BIOCIMENTS AND COATINGS OF METAL IMPLANTS. LATEST APPLICATIONS INCLUDE ITS USE IN COSMETICS, TOOTHPASTE AND AESTHETIC TREATMENT TO INCREASE CONNECTIVE TISSUE (DERME) AND CONSEQUENT DECREASE OF WRINKLES.
priorityDate 2006-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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