abstract |
In the present invention there is disclosed a process for preparing 3-{2-[4-(6-fluorbenzo[d]isoxazol-3-yl)piperidin-1-yl]ethyl}-2-methyl-6,7,8,9-tetrahydro-4H--pyrido[1,2-a]pyrimidin-4-one of the general formula I by reacting 3-(2-aminoethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one of the general formula II with the compound of the general formula III, in which Y and Z represent either identical or different released groups, such as halogen or alkyl or arylsulfonyloxy in the presence of a solvent and a base. |