| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_28ecb9d2655209cb54a6fcae204d4cba |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-755 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-43
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-745
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-755
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-04 |
| filingDate |
1992-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f7cae698469aafe6b2a3dd4dcab9b20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be039b42c41bf595fd5f892a2615c441
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_03cdb17febd6c8c8cf4c4294fe7dac15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_628f1af4fee597a83a79dcabb2738077
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e3fa1a459ff7a192726fbc32f33f948d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_595e737fcaba2e8959581c5826aaf55f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01db1f9c155dfe765dc246483f5595a2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9c321a1d951b4719e4e3475f70a2c297 |
| publicationDate |
1999-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
PT-100245-B |
| titleOfInvention |
SEQUENCE OF DNA CODING A RECOMBINANT, BIOLOGICALLY ACTIVE HUMAN FACTOR VIII DERIVATIVE, RECOMBINANT EXPRESSION VECTOR, HOST CELL, PRODUCTION PROCESS OF A FACTOR VII DERIVATIVE AND FACTOR VIII DERIVATIVE |
| abstract |
A DNA sequence coding for a biologically active recombinant human factor VIII derivative, comprising a first DNA segment coding for the 90 kDa chain of human factor VIII and a second DNA segment coding for the 80 kDa chain of human factor VIII, said segments being interconnected by a linker DNA segment coding for a linker peptide of 2 to 10 amino acid residues selected from lysine and arginine; recombinant expression vector comprising such DNA sequence; host cells of animal origin transformed with such recombinant expression vector; a process for the manufacture of recombinant human factor VIII derivative; and human factor VIII derivative containing the heavy chain and the light chain linked by metal ion bond. |
| priorityDate |
1991-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |