http://rdf.ncbi.nlm.nih.gov/pubchem/patent/PL-84511-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P13-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B59-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C01B- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J23-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-32 |
| filingDate | 1973-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1976-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | PL-84511-B1 |
| titleOfInvention | Production of 3-fluoro-d-alamine[au5136973a] |
| abstract | 1380382 3-Fluoro-D-alanine MERCK & CO Inc 1 Feb 1973 [3 Feb 1972] 5087/73 Heading C2C 3-Fluoro-D-alanine is obtained by reacting fluoropyruvic acid with an optically active D- amino compound forming the corresponding D-ketimine, reacting the latter with hydrogen or deuterium in the presence of a hydrogenation catalyst forming the corresponding N-substituted 3-fluoro-D-alanine, and catalytically hydrogenolyzing the latter to remove the N- substituent and form 3-fluoro-D-alanine or 2-deutero-3-fluoro-D- alanine. Suitable D-amino compounds are R(D)-phenyl glycine which forms corresponding intermediates 2-(D-α-carboxybenzylimino)-3-fluoro-propionic acid and N-(D)- carboxybenzyl) - 3 - fluoro - D - alanine, and D-α-methylbenzylamine which forms intermediates 2 - (D - α - methylbenzylimino) - 3- fluoro - propionic acid and N - (D - α - methylbenzyl)-3-fluoro-D -alanine.n[GB1380382A] |
| priorityDate | 1972-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 50.