abstract |
1,199,037. Medicines comprising alkanolamines. IMPERIAL CHEMICAL INDUSTRIES Ltd. 10 Sept., 1968 [27 Sept., 1967], No. 43927/67. Addition to 1,078,852. Heading A5B. [Also in Division C2] Pharmaceutical compositions in standard forms comprise a compound of the formula: (alkyl optionally substituted by OH, alkoxy aryl, aryloxy, the aryl and aryloxy radicals being optionally substituted by one or more halogen atoms or alkyl or alkoxy radicals, cycloalkyl., alkenyl; R<SP>2</SP>=acyl; R<SP>3</SP>=halogen, alkylthio, aryl, aryloxy, alkoxyalkyl, hydroxyalkyl, haloalkyl, aralkyl, cycloalkyl, acyl, alkoxycarbonyl, CN) or an ester, aldehyde condensation product or acid addition salt thereof in association with a carrier. The compositions may also contain one or more other active ingredients selected from sedatives, vasodilators, diuretics, hypotensive agents, myocardial depressants, agents used in the treatment of Parkinson's disease and cardiotonic agents (e.g. phenobarbitone, meprobamate, chlorpromazine, glyceryl trinitrate, pentaerythritol tetranitrate, isosorbide dinitrate, chlorothiazide, reserpine, bethanidine, guanethidine, guinidine, benzhexol and diptalis preparations. Compositions in which the primary active ingredient possesses selective #-adrenergic blocking properties may also contain a sympathomimetic bronchodilator, e.g. isoprenaline, orciprenaline, adrenaline or ephedrinen[GB1199037A] |