http://rdf.ncbi.nlm.nih.gov/pubchem/patent/PL-437234-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_92372bcefb0073dd236f752c73f2eed2 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2400-12 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3654 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3691 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-425 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3683 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-227 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-20 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-12 |
| filingDate | 2021-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf1232f2ef73485663ce31bddcdd79af http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc983212e443fdf66b6e20f153d9d698 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e9e2fed867493af4f209a7e72d679f7e |
| publicationDate | 2021-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | PL-437234-A1 |
| titleOfInvention | Two-phase biomaterial based on curdlane and hydroxyapatite (HAp) for the regeneration of cartilage and bone defects and the method of its preparation |
| abstract | The subject of the application is a curdlan-based biomaterial which is β-1,3-glucan (curdlate), whey protein isolate (WPI) and hydroxyapatite ceramics (HAp), where the proportions of polymer components to 100 ml of aqueous solution are respectively: 6 - 20%) (w / v) - β-1,3-glucan, 20 - 50% (w / v) - whey protein isolate (WPI), while the amount of added hydroxyapatite ceramic granules (HAp) to such a polymer mixture is 40 g - 100 g The application also covers a method for the production of a two-phase biomaterial according to the invention, wherein a 20 - 50% (w / v) aqueous solution of whey protein isolate (WPI), preferably 30% (w / v), is added to the β-1 powder. 3-glucan (curdlate), so as to obtain a mixture in which the concentration of curdane relative to the WPI solution is 6 - 20% (w / v), preferably 8% (w / v), then hydroxyapatite ceramics (HAp) are added to the mixture in the form of nanopowder or powder or granules with a size of 0.01 - 1.0 mm, fired at a temperature of 500 - 1300 ° C in the amount of 40 g - 100 g per 100 ml of Kurdlan-WPI aqueous solution, preferably 70 g of granules fired at 1100-1200 ° C, then the obtained mixture is subjected to centrifugation for 1-10 minutes at the speed 800-10 000 rpm, then the mixture with the upper - polymeric and lower - polymer - ceramic phases is incubated for about 15 minutes at the temperature of 90 - 120 ° C. |
| priorityDate | 2021-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
| Predicate | Subject |
|---|---|
| isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID64689 http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID419589780 |
Total number of triples: 28.