http://rdf.ncbi.nlm.nih.gov/pubchem/patent/PL-436291-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6728292a022c6c19233992ea183f2374 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C249-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C11B9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C251-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C43-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C251-48 |
| filingDate | 2020-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5933f3f2e2710e6f6a3fbcc8921580ae http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e406c2cc7845bbe022f3d04525e6accd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7bd8db936cf97b8e54aa6aee36cc48e2 |
| publicationDate | 2022-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | PL-436291-A1 |
| titleOfInvention | Etheric aromatic compounds and method of production |
| abstract | The invention discloses aromatic ether compounds which are citral oxime O-n-propyl ether of formula IA, wherein R <sub> 1 </sub> is a geranyl, 2-phenylethyl, 2- [1,3,3-trimethylcyclohex-1-eno] group. ethyl, (4S) -isopropenylcyclohex-1-ene, 1-aryl-1-methylmethinone, 4- [2,6,6-trimethylbicyclo [3.1.1] hept-2-ene] or a dihydrojasmone or (+) - dihydrocarone moiety , R <sub> 2 </sub> is hydrogen, methyl, 4 [2,6,6-trimethylbicyclo [3.1.1] hept-2-ene]; or a (+) - dihydrocarcon moiety, a dihydrojasmone moiety, and R <sub> 3 </sub> is n-propyl, ethyl, methyl or propargyl. The invention also relates to a process for the preparation of the aromatic ether compounds of formula IA, wherein the volatile carbonyl oxime is O-alkylated with methyl iodide, ethyl iodide, n-propyl iodide, o-a11yl bromide and o-propargyl bromide, respectively, in the presence of a hydride. sodium hydride, first, the oxime is stirred at room temperature with the solvent, which is dimethylsulfoxide, then sodium hydride is gradually introduced into the solution, and after complete hydrogen evolution, an alkyl halide is added dropwise and the reaction is carried out for at least two hours, then the reaction mixture diluted with water until the turbulence ceased, the resulting solution was further extracted with a water-immiscible solvent, then the water was removed by adding a water-binding agent, which in turn was filtered off, then the residual solvents were evaporated to give the crude product. in turn under can be purified to a pure ethereal odor. |
| priorityDate | 2020-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 47.