abstract |
The invention describes a process for the production of diastereomerically pure O- (1R, 2S, 5R) -mentyl p-toluenesulfinate having absolute (S) configuration, which consists in that a solution of racemic p-toluenesulfinyl chloride and enantiomerically pure (1S, 2R, 5S) - menthol is left to stand at room temperature for 14 days, after which the diastereomerically pure, levorotatory O- (1R, 2S, 5R) -mentyl (-) - (S) -p-toluenesulfinate formed is isolated by removing only the hydrogen chloride evolved from the reaction. |