http://rdf.ncbi.nlm.nih.gov/pubchem/patent/PL-416802-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b49b25798cc9813e3f4a0fbe099b95ab |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D221-22 |
| filingDate | 2016-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4317b526075cec66304dc794a4886449 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bcc904fe53a98bbb015dd654ff2249d4 |
| publicationDate | 2017-01-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | PL-416802-A1 |
| titleOfInvention | Chiral sulfinamides (1S, 4S, 5R) -2 - [(S) -1-phenylethyl] -4-amino-2-azabicyclo [3.2.1] octane derivatives and the method of obtaining them |
| abstract | The subject of the application are chiral sulfinamides (1S, 4S, 5R) -2 - [(S) -1-phenylethyl] -4-amino-2-azabicyclo [3.2.1] octane derivatives which are used in asymmetric synthesis as chiral auxiliaries and organocatalysts and in the synthesis of compounds of biological importance. The method of obtaining sulfinamides of (1S, 4S, 5R) -2 - [(S) -1-phenylethyl] -4-amino-2-azabicyclo [3.2.1] octane derivatives of formula 1 consists in the reaction of at least one molar part ( 1S, 4S, 5R) -2 - [(S) -1-phenylethyl] -4-amino-2-azabicyclo [3.2.1] octane with at least one molar part of 4-methylphenylsulfonyl chloride in the presence of at least one molar part of triphenylphosphine and at least one molar part of a base selected from the group: KOH, Et3N, pyridine, wherein the reactions are carried out in a solvent in the temperature range 250 - 320 K. |
| priorityDate | 2016-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 21.