http://rdf.ncbi.nlm.nih.gov/pubchem/patent/PL-416024-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cd93bb1b16087383c339db5f119a5094 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D237-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D237-26 |
| filingDate | 2016-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d42b1cddadac8b683ac912c97e256d8a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c7610168cfc3ed7cf9c89b6d39154288 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0001e31d84cdad56a1fb3197b453ab52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f9a4540a9ba7a03194c9516d92af8138 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d0fbc4339c0b40b35b1e535ed0931718 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_65348c750d3f46ef9468d81ce7bdfa27 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_165364e35c7337bcabfe70d7b44a9d8c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d83c68cf3ea6f60f89453ff7f74a6fb5 |
| publicationDate | 2017-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | PL-416024-A1 |
| titleOfInvention | Method for the preparation of mono-substituted 2,7-dihydro-3H-dibenzo [de, h] cinnoline-3,7-dione derivatives |
| abstract | The subject of the application is a process for the preparation of mono-substituted antrapiridazone derivatives of formula (I), wherein R1 is - (CH2) q-N (R4) -R5, where q = 2 or 3; R4 and R5 are the same and represent C1-C3-alkyl, or R4 and R5 together with the nitrogen atom in the 2-position to which they are attached form a 6-membered cyclic ring optionally containing an additional nitrogen or oxygen atom, such as a piperazine ring, piperidine or morpholine. The method consists in the fact that 6-chloro-2,7-dihydro-3H-dibenzo [de, h] cinnoline-3,7-dione is subjected to an N-alkylation reaction with an alkylaminoalkyl chloride of formula Cl- (CH2) qN (R4) -R5, in which q, R4 and R5 have the same meaning as in formula (I), or a salt thereof, in the presence of an acid binding agent, preferably potassium carbonate. |
| priorityDate | 2016-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.