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publicationDate 2017-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber PL-413942-A1
titleOfInvention A method for producing optically pure (+) - (R) -7-hydroxyflavanone
abstract It was revealed that as a result of the enzymatic system contained in the cells of the Aspergillus niger IBR strain, de-esterification occurs at C-7. The product thus obtained is separated from the aqueous culture of the microorganism in a known manner by extraction with a water-immiscible organic solvent (ethyl acetate). The result is (+) - (R) -7-hydroxyflavanone with an enantiomeric excess of 100% ee, at room temperature and at the natural pH for the strain.
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