http://rdf.ncbi.nlm.nih.gov/pubchem/patent/PL-400079-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7339501040a829287a6ee236092a9e00 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-52 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D235-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-20 |
filingDate | 2012-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_411b97457d71a131308f7c6e73a615e7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a7c8f684eac37c7cdc9975c1fe22821 |
publicationDate | 2014-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | PL-400079-A1 |
titleOfInvention | Method for the preparation of optically active derivatives of 1- (2-benzimidazolylsulfanyl) propan-2-ol |
abstract | The method of obtaining (R) and (S) enantiomers of 1- (2-benzimidazolylsulfanyl) propan-2-ol derivatives of general formulas 1 and 2, in which: R1 is hydrogen, methyl or ethyl, R2 is methyl or ethyl, R3 is a hydrogen atom or a halogenomethylsulfonyl group of formula 3 in which X = Cl, F and = 1,2,3, R4 is a hydrogen atom, acyl, benzoyl or carboxyethylcarbonyl group, consists in the fact that racemic 1- (2- benzimidazolylsulfanyl) propan-2-ol of formula 4, in which R1, R2, R3 have the meaning given above and R4 is a hydrogen atom, undergoes enzymatic transesterification with carboxylic acid esters of lipases, while R4 is an acyl, benzoyl or carboxyethylcarbonyl group, is subjected to enzymatic hydrolysis against lipases. |
priorityDate | 2012-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 57.