| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c902faf6ae746c51fc8010672fc22894 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C59-72
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C59-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C405-0016
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-935 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5575
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P27-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-935
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C59-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-83
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C59-72
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C405-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C59-54 |
| filingDate |
2002-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c8dbbcf641315b9a6bcf2bffe2aae180 |
| publicationDate |
2005-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
PL-366372-A1 |
| titleOfInvention |
Method and intermediates for the production of latanoprost |
| abstract |
The present invention is a novel intermediate, compound of the formula (VI)and salts thereof. In addition, the invention includes a process for the preparation of a 15(S)-prostaglandin intermediates compounds (IV) and (XVIII) which comprises (1) contacting a the corresponding enone with (-)-chlorodiisopinocampheylborane while maintaining the reaction mixture temperature in the range of from about -50° to about 0° and (2) contacting the reaction mixture of step (1) with a boron complexing agent. |
| priorityDate |
2001-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |