http://rdf.ncbi.nlm.nih.gov/pubchem/patent/PL-229133-B1

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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7048
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-727
filingDate 2015-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dbf72100de806583192590328e4be8d0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_87b2dcf5983905bc8604963d4079e84c
publicationDate 2018-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber PL-229133-B1
titleOfInvention A bioavailable composition of flavonoids containing rhamnose and its use
abstract The subject of the invention is a bioavailable composition of rhamnose-containing flavonoids consisting of a flavonoid used in an amount of 0.1 mg - 1 g per aglycone selected from the group consisting of diosmin, hesperidin or a mixture of diosmin and hesperidin and a microencapsulated fructooligosaccharide enzyme with β-ramnoside activity. and ß-glucosidase, preferably in the form of naringinase, the content of which in the composition is sufficient to produce 10-75% diosmetin from diosmin or hesperetin from hesperidin. The enzyme is microencapsulated by spray drying with fructo-oligosaccharides, keeping the ratio of enzyme to fracto-oligosaccharides in the range from 1: 0.25 to 1:20. The subject of the invention is also the use of the compositions in the production of medicinal products and nutritional preparations intended for the prevention and treatment of cardiovascular diseases, in particular chronic venous insufficiency, peripheral vascular diseases, lymphoedema, hemorrhoids, varicose veins, pressure ulcers or venous leg ulcers. The composition is used in medicinal products or nutritional preparations in the form of coated or uncoated tablets, effervescent tablets, orodispersible tablets, soft or hard capsules, powder sachets, pellets or granules.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3848018-A1
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http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021140228-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021140229-A1
priorityDate 2015-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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