http://rdf.ncbi.nlm.nih.gov/pubchem/patent/PL-213159-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e9820324809a2f50764cdd14313675dc |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12R2001-19 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-205 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-245 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-18 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18 |
| filingDate | 2010-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bec62c47b5c4e074f806bfdce84af33d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc2efe2df9fad8e85cb8011a309b3696 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eddceea8add2a099d2f84dd7b4d5aaf2 |
| publicationDate | 2013-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | PL-213159-B1 |
| titleOfInvention | Mutated strains of Escherichia coli, a method of testing potential antibacterial compounds using these strains and a test kit |
| abstract | The subject of the present invention are mutant strains of Escherichia coli MG6165 (ATCC nr 47076) lacking all potassium transporters: Kdp, Kup and Trk (ΔKtrans), encompassing strains lacking at least one of the genes encoding mechanically gated channels mscS and mscL (ΔKtrans ΔmscS i/lub ΔmscL). In particular, it concerns Escherichia coli MG61655 (ATCC No. 47076) lacking all potassium transporters: Kdp, Kup and Trk (ΔKtrans), which additionally are devoid of the mechanically gated channel gene mscS—E. coli (ΔKtrans ΔmscS), the mechanically gated channel gene mscL—E. coli (ΔKtrans ΔmscL) and/or both the mechanically gated channel genes mscS and mscL—E. coli (ΔKtrans ΔmscS ΔmscL). The subject of the present invention is also a method of testing chemical compounds for potential antibacterial properties, making use of the abovementioned strains. Another subject of the present invention is a kit for testing chemical compounds as potential antibacterial substances, containing the abovementioned strains. |
| priorityDate | 2010-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 35.