Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3be2429bd1a83fd492acffa31808839c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_89b60e340c7765626013119f28c35bfd |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-06 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-073 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-06 |
filingDate |
2002-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f39f9bbb3e7c8b26d3d85a31f876ef55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5146666042fc99ab81ce4a9a76eb0b65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2761df0583e47a3844ac3551fbe1a758 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2000a92537b43cf8853e46df81f1392d |
publicationDate |
2011-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
PL-210150-B1 |
titleOfInvention |
Production method of (E) -5- (2-bromovinyl) -2'-deoxyuridine |
abstract |
The present invention relates to the preparation of (E)-5-(2-bromovynyl)-2'-deoxyuridine (Brivudine) characterized in that halogen-free solvents selected form esters or cyclic ethers are used in the bromination step of 5-ethyl-2'-deoxyuridine diacylate. The use of said solvents is advantageous in respect of toxicity, discharge costs and environment protection. |
priorityDate |
2001-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |