| abstract |
To provide a compound which has an anticoagulation action based upon inhibition of activated blood coagulation factor X and is useful as an anticoagulant or an agent for prevention and treatment of diseases caused by thrombus or embolus. A diazepan derivative such as 4-Ä(3-carbamimidoylphenylamino)methylÜ-3-Ä4-(4-methyl-1,4-diazepan-1-y l)benzoylaminoÜbenzoic acid and 3-hydroxy-4'-methoxy-2-äÄ4-(4-methyl-1,4-diazepan-1-yl)benzoylÜaminoüb enzanilide or a salt thereof is an effective ingredient. |