| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c834eb81d6424e6d4f4cefe9cd06e34d |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-108
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2840-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2840-203
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-53 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-76
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 |
| filingDate |
2002-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d9d4dd4ab603520eb6ab73fb4777db8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b9da76923f379dae86f44e8cd8038ddb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8acfba52224ab8f4588bbe052bc322a3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc778fdce1e3b72bdb66769bf6764873
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_91e2c54fbc838ddcf86cb17c247f5fd5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_90f15d37bf6b425db08bce07f0f79d2b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc927ee0ad59202d8a8f2d9a955f9ca9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d4ebd2fb99145078371a9fb7e896afb8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f67cc182530d5e1d3a0b012b03a84b22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_17eaffe3001de83429a21d32ca4dcfb2 |
| publicationDate |
2010-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
PL-206097-B1 |
| titleOfInvention |
Expression vector, its use, method of producing this vector, host cell, pharmaceutical composition, DNA vaccine, gene therapeutic agent and method of producing DNA vaccine |
| abstract |
The present invention relates to novel vectors, to DNA vaccines and gene therapeutics containing said vectors, to methods for the preparation of the vectors and DNA vaccines and gene therapeutics containing the vectors, and to therapeutic uses of said vectors. More specifically, the present invention relates to novel vectors comprising (a) an expression cassette of a gene of a nuclear-anchoring protein, which contains (i) a DNA binding domain capable of binding to a specific DNA sequence and (ii) a functional domain capable of binding to a nuclear component and (b) a multimerized DNA sequence forming a binding site for the anchoring protein, and optionally (c) one or more expression cassettes of a DNA sequence of interest. In particular the invention relates to vectors that lack a papilloma virus origin of replication. The nuclear-anchoring protein might be the E2 protein of Bovine Papilloma Virus type 1 or Epstein-Barr Virus Nuclear Antigen 1. The invention also relates to vectors that lack an origin of replication functional in a mammalian cell. The invention further relates to methods for expressing a DNA sequence of interest in a subject. |
| priorityDate |
2001-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |