http://rdf.ncbi.nlm.nih.gov/pubchem/patent/PL-201540-B1

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inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7d577140ebe1edf3eb310afec7dfb9cf
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publicationDate 2009-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber PL-201540-B1
titleOfInvention Method for producing high purity N- (4-cyano-3-trifluoromethylphenyl) -3- (4-fluorophenylsulfonyl) -2-hydroxy-2-methylpropanamide
abstract N-(4-Cyano-3-trifluoromethylphenyl)-3-(4­fluorophenylsulfonyl)-2-hydroxy-2-methylpropanamide of high purity is produced by oxidation of N-(4-cyano-3­trifluoromethylphenyl)-3-(4-fluorophenylthio)-2-hydroxy-2­methylpropanamide, using urea-hydrogen peroxide complex (UHP), in a mixture of a C1_4-carboxylic acid and an organic solvent, as the oxidizing reagent. N-(4-Cyano-3-trifluoromethylphenyl)-3-(4­fluorophenylsulfonyl)-2-hydroxy-2-methylpropanamide is a known antiandrogen.
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