http://rdf.ncbi.nlm.nih.gov/pubchem/patent/PL-198079-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a2901e694724c2a759f619944cb7d2a4 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-4709 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-02 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4711 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-542 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6896 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-542 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 |
| filingDate | 1998-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1131de951bcbf0134cb1858a4c791928 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b949cc1c4708d4edbda40c50e0c3b186 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3076c06b86398b79c8c62d9f531bbb3d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6a3e633f026c7b89272aab2c7ab910ae |
| publicationDate | 2008-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | PL-198079-B1 |
| titleOfInvention | A method for detecting or isolating compounds capable of inhibiting the interaction between presenilin and ß-amyloid peptide precursor and / or ß-amyloid peptide and a method for testing the interaction between presenilin and ß-amyloid peptide precursor and / or ß-amyloid peptide |
| abstract | A new polypeptide (I) is able to at least partly inhibit the interaction between a presenilin (PS) and a beta -amyloid peptide ( beta A) and/or its precursor, amyloid precursor protein (APP). Independent claims are also included for the following: (a) compounds (II) that are not exclusively peptides, with the same activity as (I) obtained by reproducing the active motifs of (I); (b) a nucleic acid (III) encoding (I) or (II); (c) a recombinant defective virus or vector containing (III); (d) an expression cassette usable in the vector of (c); (e) a host cell transformed with (III); (f) recombinant production of (I) or (II) by culturing cells of (e); (g) an antibody, or its fragments, directed against peptides (IV; 87 amino acids), (V; 81 amino acids) or fragments of (VI; 695 amino acids) able to inhibit interaction between PS and beta A or APP; (h) methods for identifying or isolating compounds that can inhibit an interaction between PS and beta A or APP; (i) a method for detecting interaction between PS and beta A or APP by fluorescence transfer between two bound fluorophores; and (j) ligands of (I), (II), PS, beta A or APP identified by these methods. |
| priorityDate | 1997-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 479.