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filingDate 1999-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b8d4e3fb4a2cea5cc690abc85047f131
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publicationDate 2007-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber PL-195582-B1
titleOfInvention The iron (III) oxyhydroxide and hydrogenated dextran association complex, the method for producing this complex, the use of this complex and the method for producing an injection fluid containing this complex
abstract An iron-dextran compound for parenteral treatment of iron-deficiency anemia comprises hydrogenated dextran having a weight average molecular weight (Mw) between 700 and 1,400 Daltons, preferably approximately 1,000 Daltons, a number average molecular weight (Mn) of 400 to 1,400 Daltons and wherein 90 % by weight of the dextran has molecular weights less than 2,700 Daltons and the Mw of the 10 % by weight fraction of the dextran having the highest molecular weights is below 3,200 Daltons, said hydrogenated dextran having been subjected to purification by membrane processes having a cut-off value between 340 and 800 Daltons, in stable association with ferric oxyhydroxide. The compound is produced by using membrane processes to eliminate dextrans of higher molecular weights than approximately 2,700 Daltons and membrane processes to remove saccharides of molecular weights below approximately 340 Daltons from hydrogenated dextran before precipitating ferric hydroxide in the presence of said dextran followed by heat treatment and purification.
priorityDate 1998-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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