http://rdf.ncbi.nlm.nih.gov/pubchem/patent/PL-194665-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_43d9709cc9e5268a7f5549968dc871b5 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-66 |
| filingDate | 2000-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3b37e59e1423bf2303fb969db662c75b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b4e43706b87fb6ad3277fa354aaf6d11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0817533cf15a90ceed3f3700e39d43ad |
| publicationDate | 2007-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | PL-194665-B1 |
| titleOfInvention | The method of obtaining homochelidonin from celandine root |
| abstract | 1. Method of obtaining homochelidonine from celandine root by countercurrent extractionnshredded plant material with an aqueous solution of organic acid, sorption of alkaloids onnsilica gel and selectively eluting them, characterized in that the obtained leakage after passing throughnof the extract with a pH of 5.5-6.5, preferably 6.0 through a column of silica gel, is made alkalinento a pH of at least 8.5 with potassium hydroxide, preferably sodium hydroxide, and the precipitated alkaloidsnis suction filtered, then treated with 100% methanol in a proportion of 1 part by volumensediment to 1 - 3, preferably 2 parts of methanol, then the solid not dissolved in methanol is filtered offnunder vacuum and dissolve in excess methanol, preferably in the amount of 1 part of the precipitate, 6 parts of methanol,nand then homochelidonine crystals are crystallized, which are optionally recrystallized,nwhile alkaloids, mainly protopin, are preferably recovered from the methanol solution from the supernatant,nchelidonine and allocryptopine by known methods, for example by crystallization. |
| priorityDate | 2000-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 35.