| abstract |
Comprises an inert nucleus; an active layer which is soluble or disintegrates rapidly in water, obtained from a single aqueous or hydroalcoholic solution-suspension which includes: an active ingredient of anti-ulcerous activity of formula I, II or III, and at least one excipient; and a gastro-resistant outer coating layer obtained from a solution which includes an enteric coating polymer and at least one excipient. The procedure is carried out by 1) coating of the inert nuclei by spraying of a single aqueous or hydroalcoholic suspension-solution; 2) drying of the active layer formed during the spraying of the previous stage; and 3) coating of the charged nuclei by spraying of a solution which includes an enteric coating polymer with at least one excipient in order to obtain a gastro-resistant outer coating layer. <IMAGE> |