| abstract |
The invention discloses a device for transdermal administering of two active principles (I) and (II) constituted in two compartments (A) and (B), compartment (A) containing a matrix loaded with (I), and compartment (B) containing a matrix loaded with (II), each of these matrices being respectively coated with a protective film, identical in nature or not, (a) and (a'), characterised in that (A) is separated from (B) by an empty space of 1 to 10 mm and characterised in that (A) and (B) are supported by the same seelable protective film (b). Their method of preparation and their application as medicine are also disclosed. |