http://rdf.ncbi.nlm.nih.gov/pubchem/patent/PL-180253-B1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_55caf477e1bf47c3ae320a2aae2e9c92 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f1a3a291c372a6fed6d923d3c3ae9273 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H17-08 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7042 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 |
filingDate | 1995-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2001-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | PL-180253-B1 |
titleOfInvention | N-methyl-N-glycosyl derivatives of methyl esters of polyene macrolide antibiotics and their salts and their preparation EN EN EN EN EN EN |
abstract | The invention relates to N-alkyl-N-glycosyl derivatives of alkyl esters of antifungal antibiotics of polyene macrolide group of general formula (1a), wherein M represents polyene macrolide antibiotics residues, R represents a variable part of sugar residue, and each of R<1> and R<2> represents a C1-4 alkyl group; their salts of general formula (2a), wherein R, R<1>, R<2> and M are as herein defined and A represents an anion of organic or inorganic acid. Compounds of formula (1b) and (2b) wherein the N-alkyl and alkyl ester groups are represented by methyl are of particular interest. The invention relates also to processes for preparation of the compounds, to compositions containing these compounds and to their use in therapy and the treatment of external and internal fungal infections in humans and animals. |
priorityDate | 1995-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 102.