http://rdf.ncbi.nlm.nih.gov/pubchem/patent/PL-179597-B1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_46830b651781109964ac264c9d707376 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P15-08 |
filingDate | 1995-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_582b6d8969bb5e0fade4cc9be5b8f55a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c3e5cbcc572d7593dc22c3d96a21c16b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d79e2904205b7e790b314b3a695f4b94 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_291ac5384ed62187ad3973a181ec8b7a |
publicationDate | 2000-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | PL-179597-B1 |
titleOfInvention | A method of obtaining high purity acetate peptide-analogues of LHRH |
abstract | 1. A method of obtaining high-quality LHRH peptide analogues acetatenthe formula pGlu-Hit-Trp-Ser-Tyr-Q-Leu-Arg-Pro-X, where Q is D-Leu, O- (1,1-dimethylethyl) -D-Ser,n3- (2-naphthyl) -D-Ala, 1- (phenylmethyl) -D-Ser, D-Trp, and X isnGly, NHC2H5 or NH-NH-CO-NH2, characterized in that the crude peptide of formula givennabove undergoes reverse-phase high performance liquid chromatography (HPLC),nusing a gradient system of solvents A and B as the mobile phase, where the solventnA is a 0.5 to 2 vol% free acetic acid solution, anSolvent B consists of 50 to 100% by volume of a polar organic solventna mixture of wooa, selected from methanol, ethanohi, accton, acctomtryl and tetrahydrofuran,n0 to 49.5% by volume water and 0 to 2% by volume acetic acid. |
priorityDate | 1995-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 60.