http://rdf.ncbi.nlm.nih.gov/pubchem/patent/PL-176409-B1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cf32b60391b469c41e86c353437f5751 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-535 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-18 |
filingDate | 1994-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2804ee9a9daf3ebc14cff4ca9b719c25 |
publicationDate | 1999-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | PL-176409-B1 |
titleOfInvention | Tetrahydropyran derivatives, the method of their preparation and the pharmaceutical composition containing them |
abstract | CLAIMS 1. Tetrahydropyran derivatives of formula I in which R 1 is a group of formula 2 or 3, in which or R 7 is optionally protected hydroxyl, acyloxy, halogen, -OR 10, in which R 10 is lower alkyl, optionally protected by the -O (CH2) mOH group, where m is a number 2-4, or the group -OCONH2, and R7a is hydrogen, or R7 and R7a together are oxo, R8 is a hydroxyl or methoxy group, and R9 is hydroxy or acyloxy; R2 is hydrogen, acyloxy, or an optionally substituted hydroxy group, and there is a single or double bond between the two carbon atoms joined by a dashed line; R 3 is methyl, ethyl, n-propyl, or allyl; or R 4 is hydrogen or hydroxy and R 4a is hydrogen, or R 4 and R 4a together are oxo; or R 5 is hydroxy and R 5a is hydrogen, or R 5 and R 5a together are oxo; and A is a group of formula -CH (OR 6) -CH2- (CN2) n- or -CH = CH- (CH2) n-, in which the (CH2) n- portion is attached to the carbon atom, R6 is the lower group alkyl and n is 1 or 2; in free form, and wherever they exist, in salt form. PATTERN 1 PL |
priorityDate | 1993-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 39.