abstract |
A process for the preparation of ethyl apovinaminate of the formula 1, characterized by reacting apovincamic acid of the formula 2 with ethanol in the presence of a catalyst which is a penta fluorobenzene derivative of the general formula 3, in which X is the group - OCH3, -CHOCH3, -NO2, -CH3 or CN, in a polar organic solvent, in the presence of an organic base at room temperature. W ZÓ R 1 PL |