abstract |
1. A process for the preparation of 1,2,3,9-tetrahydro-9-methyl-3 - [(2-methyl-1H-imidazol-1-methyl] -4H-4-carbazolone-4 of the formula I, characterized by 2- [2- (2- (methyl--1H-imidazole-1) methyl] -4- (1-methylindolyl-2) -butyric acid of formula 2 is cyclized under Friedel Crafts acylation reaction conditions, activating the carboxyl group by acid catalysis in a suitable solvent and isolation of the desired product by known methods. Formula 2 PL |