http://rdf.ncbi.nlm.nih.gov/pubchem/patent/PL-170324-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5929f2d6f4dba84be8dd3a8ba633db12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-415 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D235-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D235-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D235-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D235-26 |
| filingDate | 1991-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ce64357337d9418efc856bb31107df44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9268b7cc3c959d694be1485238cddb45 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_08371a19d0d2f12c3a131e895454cac5 |
| publicationDate | 1996-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | PL-170324-B1 |
| titleOfInvention | Method for the production of new benzimidazole derivatives PL |
| abstract | The present invention relates to benzimidazole derivatives of the general formula I, in which the ring A represents a benzene ring that can optionally contain, in addition to the group R also other substituents, Re1 represents hydrogen or an optionally substituted hydrocarbon radical, Re2 represents a group being capable to form anion or a group that is convertible thereto, X represents a straight bond or a group between a phenylene group and a phenyl group with atomic length at the most 2, R represents a carboxyl group, further ester or amide thereof or a group being capable to form anion or a group convertible thereto, Y represents -O-, -S(O)im- or -N(Re4)-, wherein m is 0, 1 or 2 and Re4 represents hydrogen or an optionally substituted alkyl group and n is 1 or 2 as well as their pharmaceutically acceptable salts. The above-described derivatives and pharmaceutically acceptable salts thereof exhibit a valuable antihypertensive and antagonistic activity against angiotensin II and they are therefore usable as pharmaceutical preparations for treating circulation diseases such as hypertension and heart diseases. In the present invention there is also claimed a process for preparing these derivatives and intermediates for their preparation. |
| priorityDate | 1990-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 160.