http://rdf.ncbi.nlm.nih.gov/pubchem/patent/PL-169867-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_536f001e42b4421737473b6644539991 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-655 |
| filingDate | 1992-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9fe907bcf0bebec9f84c5ee40a36b0f8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c0ae0a2b74c35390737bac7a6976e74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_27e3daddfd69da5d71bbc2ac7237da5f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3cd1e85f7f71e26f13e24361863e2030 |
| publicationDate | 1996-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | PL-169867-B1 |
| titleOfInvention | A method of obtaining new somatostatin analogues showing growth hormone release inhibition properties |
| abstract | 1. The method of obtaining new analogsn© somatostatin heads, showing propertiesninhibiting the release of growth hormone onformula 7, wherein X is a constitutive moietynH or NH2 or CH2-CH2-NH2 ornCH2-CH2-OH or C (CH2OH2CHa, and Y isnthe residue given in formula 3 or formula 4 ornFormula 5 or Formula 6 wherein the compoundnof general formula 10 is deposited on the resinnMerrifield, is acylated withna compound of formula 11 or formula 12 or formulan13 or formula 14 is removed from the resin by reactionnaminolysis with the compound NH2Χ, wherenX is as defined above and groups are removednprotective in the reduction reaction with sodium in liquidnammonia and oxidized with 0.01na molar aqueous solution of ferrocyanidenpotassium or 0.1 molar iodine solutionnin methanol. |
| priorityDate | 1992-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 156.