http://rdf.ncbi.nlm.nih.gov/pubchem/patent/PL-167058-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_96ac0342a3ccf9553e3d4c9da9b821b0 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 |
| filingDate | 1990-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_876f275df5dc9bbf3f1bf801cd4a7c05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0a2e7be2120830a187284b98df612647 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3b1e607eed842e9262d52d246c0548f8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_84a37c08bc3fb7a460f37f80e09eec9d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c4023a4e68ff4ffef269ec923478dda4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d9ea2f588a32ff4d7ff98878f6200dea http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7fe05e7fab7f6d6a88055352078aed66 |
| publicationDate | 1995-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | PL-167058-B1 |
| titleOfInvention | A method of producing a polypeptide that is a fragment of a human protein C capable of producing antibodies that react specifically with human protein C and the polypeptide and / or react specifically with antibodies for the polypeptide |
| abstract | 1. A method of producing a protein C fragment polypeptide capable of inAntibodies that react specifically with and / or react with human protein C and this polypeptidenspecifically with antibodies to said polypeptide characterized in that the recombinant vector containsnDNA encoding a polypeptide of formula (Y) a- (X) c-A- (Z) b is transformed into bacterial host cells,nwhich are cultivated and the protein of formula (Y) a- (H) c-A- (Z) b is isolated therefrom, which is optionally broken intonfragments of the formulas (Y) a- (X) c- and -A- (Z) b, where in the above formulas Y is a carrier proteinnencoded by a vector fragment, preferably Met 1 -Val 444 β-galactosidase and / or a sequence encoded byna polylinker fragment, preferably Gln, Gly, Leu, Glu; a is 0 or 1, X is a linker peptide, preferablynPhe, Asp, Pro; c is 0 or 1, A is the sequence corresponding to a fragment of human protein C,ncomprising the amino acids at positions 56-119 of the heavy chain of human protein C as follows:n- Met-Asp-Glu-Ser-Lysn61: -Lys-Leu-Leu-Val-Arg-Leu-Gly-Glu-Tyr-Aspn71: -Leu-Arg-Arg-Trp-Glu-Lys-Trp-Glu-Leu-Aspn81: -Leu-Asp-Ile-Lys-Glu-Val-Phe-Val-His-Pron91: -Asn-Tyr-Ser-Lys-Ser-Thr-Thr-Asp-Asn-Aspn101: -Ile-Ala-Leu-Leu-His-Leu-Ala-Gln-Pro-Alan111: -Thr-Leu-Ser-GIn-Thr-Ile-Val-Pro-Ile-,nZ is a complementary sequence, preferably Met, and / or a sequence encoded by a polylinker fragment, bnis 0 or 1. |
| priorityDate | 1990-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 289.