http://rdf.ncbi.nlm.nih.gov/pubchem/patent/PL-166731-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_42e94091a4fc81b8d0237117707cc7ee |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
| filingDate | 1991-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7655586d45fa36466cacaae8734d5bba http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5bf7924c3134ad851f9ecaa0d2c1919a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1259adce704cac9cbbb38ff164999371 |
| publicationDate | 1995-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | PL-166731-B1 |
| titleOfInvention | A method of producing a composition for the treatment of infections caused by organisms sensitive to β-lactam antibiotics |
| abstract | 1. A method of making an agent for treating an infection caused by an organismnsensitive to β-lactam antibiotics, based on the oligopeptide and β-lactam antibiotic,ncharacterized in that the cationic amphipathic oligopeptide is isolated and purified,nforming an α-helical structure with a sequence of residues in the presence of a lipid / water interfacenamino acid aai-Leu-Tyr-Lys-Lys-aa2-aa2-Lys-Lys-Leu-aa3-aa4-X wherein aa; meansnPro, Ala or Lys, aa2 is Ile, or Leu, aa3 is Glu or Lys, aa4 is Ser, Leunor Lys and X is a carboxy group or a sequence of five amino acid residues onthe α-helical structure defined by the general amino acid sequence aa5-Lys-Lys-aa ^ -Gly, innwhere aa5 is Ala or Leu and aa6 is Leu or Phe and so isolated and purifiednthe oligopeptide binds to the β-lactam antibiotic. |
| priorityDate | 1991-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 92.