http://rdf.ncbi.nlm.nih.gov/pubchem/patent/PL-165249-B1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9121d09077c19b284c0dcef92f5b361d |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0036 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D519-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0052 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0071 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D519-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D257-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C279-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-555 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 |
filingDate | 1991-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ecbbc77fa3fdafd7faa906e74e3d891f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f1df55f65a739dbee5544791d250ad2 |
publicationDate | 1994-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | PL-165249-B1 |
titleOfInvention | Method for obtaining complex salts of hematoporphyrin and its derivatives PL PL PL PL PL PL PL |
abstract | New complex salts of hematoporphyrin and of its derivatives have general formula 1, <CHEM> in which R<1> and R<2> are identical or different and denote the -CH=CH<6>, -CH/OH/-CH<7> or CH/OR<3>/-CH<7> groups, where R<3> represents the group forming the oligomer containing ethereal and/or ester bindings, this group comprising from 1 to 5 identical or different units derived from monomer of formula 2 or R<1> and R<2> are identical and denote the CH/R4/-CH<7> group, where R4 represents the groups: carboxymethylamino, 1-carboxypenthylamino, 1-carboxy-2-methylpropylamino, 1-carboxy-3-methyl-butylamino, 1-carboxy-2-methyl-butylamino, 1-carboxybutylamino, 1-carboxypentylamino, 1-carboxy-2-hydroxyethylamino, 1-carboxy-2-hydroxy-propylamino, 1-carboxy-2-mercapto-ethylamino, 1-carboxy-3-methylthio-propylamino, 1,2-dicarboxy-ethylamino, 1-carboxy-2-carbamoyl-ethylamino, 1,3-dicarboxy-propylamino, 1-carboxy-3-carbamoyl-propylamino, 1-carboxy-2-phenyl-ethylamino, 1-carboxy-2-/4-hydroxyphenyl/-ethylamino, 1-carboxy-2-indolyl-ethylamino, 2-carboxy-pyrrolidinyl, 2-carboxy-4-hydroxy-pyrrolidinyl, 1-carboxy-5-amino-pentylamino, 1-carboxy-4-guanidyl-butylamino, 1-carboxy-4-hydroxy-5-amino-pentylamino or 1-carboxy-2-/1H-imidazole/-ethylamino group; A signifies a basic amino acid; m amounts to 2-6, n is 1-5 are disclosed. The method for preparation of new complex salts of formula 1 consists of reacting, with a basic amino acid, of hematoporphyrin derivatives of general formula 4, in which R<1> and R<2> have the above-stated meaning. The new complex salts are used as a therapeutic agent for detection and treatment of neoplasms. |
priorityDate | 1991-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 88.