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filingDate 1990-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d6fcf39039c81444d227a79e812d918
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publicationDate 1993-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber PL-162446-B1
titleOfInvention Method of obtaining a diagnostic preparation for the detection of rheumatological factor in blood serum
abstract Method of obtaining a diagnostic preparation for the detection of rheumatological factorsnin the blood serum using microspheric polystyrene carriers,non the surface of which human albumin is adsorbed and human is immobilizednimmunoglobulin G, characterized in that the polystyrene support is obtained by roadnwater-emulsion polymerization of styrene in the presence of potassium persulfate and an alkanol esternand di-p-toluyl-carbinol-ortho-phenylene carboxylic acid, and then the product is subjected tonadditional gamma irradiation until the monomer is completely converted tonpolymer, and then albumin is introduced into an aqueous suspension of the thus obtained carriernhuman in an amount of 1-10 mg / ml in a phosphate buffer solution at pH 7.4, ponafter washing, add glutaraldehyde solution and add pre-warmed humannimmunoglobulin G in the amount of 0.2-10 mg / ml, then washed with glycine buffer andnpossibly conserves.
priorityDate 1990-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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