http://rdf.ncbi.nlm.nih.gov/pubchem/patent/PL-151696-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4704 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-61 |
| filingDate | 1986-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1990-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | PL-151696-B1 |
| titleOfInvention | Method of obtaining derivatives of quinolone |
| abstract | Quinolone cardiac stimulants of the formula:- …<CHEM>… or a pharmaceutically acceptable salt thereof,… wherein "Het" is a 5-membered monocyclic aromatic heterocyclic group containing at least one nitrogen atom in the aromatic ring and attached by a nitrogen atom to the 5-, 6-, 7- or 8- position of the quinolone;… "Het" being substituted by a group selected from - @-(C1-C4 alkyl), -R<1>, - @-R<1> and -@-R<2> wherein R<1> is a phenyl group optionally substituted by 1 to 3 substituents each independently selected from C1-C4 alkyl, C1-C4 alkoxy, hydroxy, halo, trifluoromethyl, -CONR<3>R<4>, -SO2NR<3>R<4>, -N(R<3>)SO2(C1-C4 alkyl) and-S(O)n(C1-C4 alkyl) where R<3> and R<4> are each H or C1-C4 alkyl and n is 0, 1 or 2, and R<2> is a heterocyclic group selected from thienyl, furyl, imidazolyl, triazolyl and tetrazolyl, said heterocyclic group being attached to the adjacent carbonyl group by a ring carbon atom and being optionally substituted by up to two substituents each independently selected from C1-C4 alkyl, C1-C4 alkoxy and halo;… "Het" also being optionally substituted by up to two C1-C4 alkyl groups;… and R, which is attached to the 5-, 6-, 7- or 8- position of the quinolone, is H, C1-C4 alkyl, C1-C4 alkoxy, hydroxy, CF3, halo, cyano or hydroxymethyl. |
| priorityDate | 1985-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 57.