| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c564804e4e89ea0871bbeefd81569950 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4709
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C229-36 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-56 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-56 |
| filingDate |
2020-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b52f85f3950a37b9358ab566e2d6d900
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c16f740931ed38a60dff00f8e4ca885
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c8c55f5d83ec1979ee66e058bc64140
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e31c09602a147e08060d2818bc723a20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_50dec44c55232f5887d79e75743eec42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a553b7cc7b23f97b97f70138722f7074 |
| publicationDate |
2021-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
PH-12020551750-A1 |
| titleOfInvention |
Process for the hydrolysis of quinolone carboxylic esters |
| abstract |
Quinolone carboxylic esters of general formula (II) are hydrolyzed to form quinolone carboxylic acids of general formula (I): the method comprises the step A): A) reacting compounds of formula (II) with a mixture that comprises acetic acid, sulfuric acid and water. In step A), = 30 to = 40 mol acetic acid, = 0.3 to = 1 mol sulfuric acid and = 0.9 to = 2.5 mol water are used per mol of compounds of formula (II). The process according to the invention is particularly suitable for the synthesis of the intermediate (I) in the synthesis of pradofloxacin. |
| priorityDate |
2018-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |