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filingDate 2019-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_efea81e4c45b634b908def22c7d16c9c
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publicationDate 2020-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber PH-12019501650-A1
titleOfInvention Hyperstabilized liposomes increase targeting of mitotic cells
abstract Hyperstable liposome comprising an anti-mitotic agent, one or more anions and one or more cations entrapped in the inner milieu, wherein the entrapped anti-mitotic drug is released at a slow rate that is less than 0.6 pcnt in 12 hours or less than 5 pcnt in 8 hours when the liposomes are suspended in 600mM sucrose. These liposomes are useful in the treatment of cancer. In particular, HEPC:Chol:DSPE-PEG2000 (50:45:5) liposomes comprising BI 2536 and citrate:phosphate in a ratio of 1 :3.
priorityDate 2017-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 31.