http://rdf.ncbi.nlm.nih.gov/pubchem/patent/PH-12018050480-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b2385552ea1fcf7f43527c6a0694826f |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-75 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-435 |
filingDate | 2018-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_09612a7e208f20c571cbe4bcc5de7f4a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a4f371e749ca0c36d6528770db216700 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b1b35a4c282abd50a58e427f54068f2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a1b52b5ce890882395835cdc58a67fa6 |
publicationDate | 2020-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | PH-12018050480-A1 |
titleOfInvention | Compositions and methods for probing and/or controlling biochemical mechanisms relating to process of blood coagulation and humoral immunity, for investigating and/or modulating said processes for health applications |
abstract | The invention provides: macromolecular peptide-based constructs comprising fibrin(ogen)-, heparin- and/or microbe-binding motifs, said constructs exemplified by polymeric peptide-based constructs and supramolecular constructs comprising immune complexes; use of said constructs for modulating blood plasma coagulation activity in the presence or absence of heparin, detecting microbes, enhancing antibody-mediated immune clearance of said microbes and/or stabilizing cell membranes; modified erythrocytes comprising inactivated anticomplement defense systems; methods for making said erythrocytes; use of said erythrocytes for detecting said complement activity; compositions comprising functional blood plasma proteins and chemically inactivated complement components; methods for making said compositions using nucleophilic agents; and use of said constructs and/or compositions in methods for treating conditions characterized by coagulopathy and/or complement-mediated pathology. |
priorityDate | 2018-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 22.