http://rdf.ncbi.nlm.nih.gov/pubchem/patent/PH-12015502435-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_382ccfc2ebebcaee15aa7cda4cee86bc |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2018 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-496 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20 |
| filingDate | 2015-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e9607006e85d75a9f0e0661a008ae935 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6455182e84486db2d763c08fdac5bbd0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e02092155cc304039adf2f17712b3bd |
| publicationDate | 2016-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | PH-12015502435-A1 |
| titleOfInvention | Oral solid preparation comprising aripiprazole and method for producing oral solid preparation comprising aripiprazole |
| abstract | An object of the present invention is to provide an oral solid preparation that can be produced in a simpler manner than conventional methods, that exhibits high bioavailability and high dissolubility even in persons having low stomach acid, and that can also ensure dissolubility after being allowed to stand for a certain period of time. Another object is to provide a simple method for producing the oral solid preparation. The present invention relates to an oral solid preparation comprising, as an active ingredient, a finely milled crystal obtained by milling an aripiprazole hydrate crystal, and a pharmaceutically acceptable carrier, the finely milled crystal having a mean particle size of 15 mm or less; an oral solid preparation comprising, as an active ingredient, a finely milled powder obtained by milling a highly hygroscopic aripiprazole anhydrous crystal, and a pharmaceutically acceptable carrier, the finely milled crystal having a mean particle size of 10 mm or less; a method for producing an oral solid preparation comprising the steps of (1) milling an aripiprazole hydrate crystal into a finely milled crystal having a mean particle size of 15 mm or less, and (2) mixing the obtained finely milled crystal with a pharmaceutically acceptable carrier; and a method for producing an oral solid preparation comprising the steps of: (1') milling a highly hygroscopic aripiprazole anhydrous crystal into a finely milled powder having a mean particle size of 10 mm or less; and (2') mixing the obtained finely milled powder with a pharmaceutically acceptable carrier. |
| priorityDate | 2013-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
| Predicate | Subject |
|---|---|
| isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID419492710 http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID60795 |
Total number of triples: 21.