| abstract |
An acetyl-CoA-producing microorganism that is obtained by imparting the activity of at least one kind of enzyme selected from the group consisting of malate thiokinase, malyl-CoA lyase, glyoxylate carboligase, 2-hydroxy-3-oxopropionate reductase and hydroxypyruvate reductase to a microorganism having none of (a), (b), (c), (d) and (e): (a) a carbonic acid fixation cycle comprising an enzymatic reaction from malonyl-CoA to malonic semialdehyde or 3-hydroxypropionic acid; (b) a carbonic acid fixation cycle comprising an enzymatic reaction from acetyl-CoA and CO2 to pyruvic acid; (c) a carbonic acid fixation cycle comprising an enzymatic reaction from crotonyl-CoA and CO2 to ethylmalonyl-CoA or glutaconyl-CoA; (d) a carbonic acid fixation cycle comprising an enzymatic reaction from CO2 to formic acid; and (e) at least one member selected from the group consisting of malate thiokinase and malyl-CoA lyase. |