http://rdf.ncbi.nlm.nih.gov/pubchem/patent/PE-66798-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-59 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C401-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F7-1804 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-59 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C401-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-10 |
| filingDate | 1997-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2bd775bbcb51d76731a9da4ba05a38a2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c3bf8277249b012830d21d12da3f2033 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c5dcf6262dde45278959fd0be4771505 |
| publicationDate | 1998-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | PE-66798-A1 |
| titleOfInvention | ANALOGS OF VITAMIN D3 TREATED WITH FLUORINE |
| abstract | THEY REFER TO COMPOUNDS OF FORMULA (I), WHERE: "X" IS = CH2 OR THEY ARE HYDROGEN; R1 AND R2 ARE OF PREFERENCE H, CF3 OR CH3, or R1 AND R2 TOGETHER WITH CARBON 20 FORM A CYCLOFLUOROALKYL OR CYCLLOALKYL C3-C6, or R1 AND R2 TOGETHER FORMAN = CH2; R3 AND R4 ARE OF PREFERENCE CH3, CF3, CH2CH3, CH2CF3, CF2CH3 AND CF2CF3 or R3 AND R4 TOGETHER WITH CARBON 25 FORM A C3-C9 CYCLOFLUOROALKYL; "A" IS A SINGLE OR DOUBLE LINK; "B" IS A DOUBLE OR TRIPLE LINK; ALWAYS THAT: WHEN "X" IS = CH2, "A" IS A DOUBLE LINK, AND: (i) R3 AND R4 ARE CF3: IF ONE OF R1 AND R2 IS H, THEN THE OTHER IS NOT CH3; (ii) R3 AND R4 ARE C1-C2 ALKYL: IF R2 IS H, THEN, R1 IS NOT CH3; (iii) R3 AND R4 ARE C1-C4 ALKYL: IF R1 IS H, THEN R2 IS NOT CH3; (iv) R1 IS CH3, R2 IS H: IF ONE OF R3 AND R4 IS CF3, THEN THE OTHER IS NOT CH3; (v) WHEN "X" IS H, R3 AND R4 ARE CF3, "A" IS A DOUBLE LINK, "B" IS A TRIPLE LINK: IF R2 IS H, THEN R1 IS NOT CH3. IT ALSO REFERS TO THE PROCEDURE FOR THE PREPARATION OF THE COMPOUNDS (I), WHICH INCLUDES THE ELIMINATION OF THE SILILO PROTECTIVE GROUPS; AND TO THE INTERMEDIATE COMPOUNDS OF FORMULA (II), WHERE: R1 AND R2 ARE CH3 or TOGETHER WITH CARBON 20 FORM A CYCLOPROPAN RING or FORMAN UN = CH2; R3, R4, "A" AND "B" ARE AS DEFINED FOR (I); "Y" IS H or OSi (CH3) 3. THE COMPOUNDS OBTAINED ARE USED TO TREAT OSTEOPOROSIS |
| priorityDate | 1996-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 33.