| abstract |
THEY REFER TO COMPOUNDS (I), WHERE: R1 IS PHENYL OR HETEROARIL, AMONG OTHERS; "W" AND C (H) pC (= X) FORM A CYCLOALKYL, HETEROCICLE, AMONG OTHERS; "X" ES = O, = S, (H, OH), (H, SH) and (H, H); "Y" IS CH (R2) -CO-NH; R2 IS ALKYL, CYCLLOALKYL, AMONG OTHERS; "Z" IS TCX`X "CO;" T "IS A LINK; X 'Y X" ARE H, OH, F or BOTH FORMAN = O; m Y p ARE 0-1; n ES 0-2; WITH THE CONDITION THAT a) WHEN R1 IS 3,5-DIFLUOROPHENYL, R2 IS CH3, "Z" IS CH2CO, m, n AND p ARE 1 THEN W AND CH AND C = X DO NOT FORM A GROUP 2- (S) -INDANOL , AMONG OTHER CONDITIONS THE COMPOUNDS (I) MAY BE USEFUL IN THE TREATMENT AND PREVENTION OF ALZHEIMER'S DISEASE |