| abstract |
THEY REFER TO COMPOUNDS OF FORMULA (I), WHERE: R1 IS PREFERRED FLUOROPHENYL, DIFLUOROPHENYL OR CYANOPHENYL; R2 IS H or C1-C6 ALKYL; R3 IS PREFERABLY CHLOROPYRIDINE or FLUOROPYRIMIDINE, AMONG OTHERS; m Y n ARE 0; 1 or 2; "X" IS O, C (O) O or CH2, AMONG OTHERS. IT ALSO REFERS TO THE INTERMEDIATE COMPOUND OF FORMULA (IV), WHERE: n IS 0 or 1; "Y" IS CH or N; "Z" IS Cl or F. THE COMPOUNDS OF FORMULA (I) ARE USEFUL IN THE TREATMENT OF DOPAMINERGIC SYSTEM DISORDERS, DUE TO THEIR AFFINITY WITH THE DOPAMINE D4 RECEPTOR |