Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_32784d1ba4f017e1fe91badd81d9ebaf http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_86bd6bf5a2cb8ba68b45b2c4a13e6b14 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-04 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-465 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04 |
filingDate |
2018-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2179c2cbfbc9183decf1fb14d70178d0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b2d2267bf2fd2cab1a649d488a0a96e9 |
publicationDate |
2021-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
PE-20211392-A1 |
titleOfInvention |
ENANTIOMERIC SEPARATION OF RACEMIC NICOTINE BY ADDITION OF AN ENANTIOMER OF TARTARIC ACID OR, O'-DISUSTITUTED |
abstract |
The present invention relates to a method for separating the racemic nicotine of formula (Ia), in the form of a mixture of the R and S enantiomers, into the enantiomerically pure (R) - and (S) -nicotine represented by formula (Ib) and formula (Ic), by adding a mixture of the L enantiomer and the D enantiomer of an O, O'-disubstituted tartaric acid, in which the molar ratio of the L enantiomer with respect to the D enantiomer is from 80:20 to 95: 5 and obtaining the (S) -nicotine of formula (Ib), or by adding O, O'-dibenzoyl-D-tartaric acid and obtaining the (R) -nicotine of formula (Ic). |
priorityDate |
2017-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |