abstract |
It refers to a method for producing diphenylmethane derivatives of the following formula 1a where A is oxygen, sulfur; n is 1 or 2; X 'is halogen or C1-7 alkyl; B is phenyl. Said compound is carried out by means of a convergent synthesis method in which each main group is synthesized separately and then coupled, in addition the crystalline form has excellent physicochemical characteristics that is effective as a sodium-dependent glucose cotransporter inhibitor ( SGLT) in the treatment of diabetes. |