| abstract |
Referring to an in vitro method to detect the genotype rs 10524523 from a biological sample, where each allele of the genotype is assigned as: a) short (S, less than 19 T residues); b) long (L, 19 to 29 residues); or c) very long (VL, 30 or more residues); and determining an increased risk of developing Alzheimer's-type cognitive impairment at a predetermined age or age range; in addition, the APOE 2 genotype of epsilon 2 / epsilon 2 or epsilon 2 / epsilon 3 is detected, indicating a non-increased risk. The method determines whether 0.5 to 9 milligrams of pioglitazone is administered. |