| abstract |
Referred to a compound of Formula (I), where m is 0, 1 or 2; Z is hydrogen, CH3 or -OR1, where R1 is selected from hydrogen, C3-C6alkenyl, haloC1-C4alkyl, - (CH2) nX, among others; n is 1, 2, 3, or 4; X is selected from hydrogen, -CH3, -CF3, C1-C4alkoxy, -N (CH3) 2, among others; A is selected from -CH2O-, -OCH2-, - (CH2) 2-, among others; and R2 is selected from (II) and (III). These compounds are immunomodulatory, useful for the treatment of various diseases, including cancer and infectious diseases. It also refers to pharmaceutical compositions, comprising this compound and a pharmaceutically acceptable agent. |