http://rdf.ncbi.nlm.nih.gov/pubchem/patent/PE-20181038-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f52c68e4149a6c462b850d4e7cc2b2f9 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4184 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D235-30 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4184 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D235-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2016-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c6ddb72f519c4ff6d10d084388f14d10 |
| publicationDate | 2018-07-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | PE-20181038-A1 |
| titleOfInvention | INHIBITOR OF MUTATED ISOCITRATE DEHYDROGENASE IDH1 R132H |
| abstract | Refers to an adduct formed by (2E) -but-2-enedioic acid and 3- (2 - {[4-4-trifluoromethoxy) phenyl] amino} -1 - [(1R, 5R) -3 acid, 3,5-trimethylcyclohexyl] -1H-benzimidazol-5-yl) propanoic acid comprising a molecule of fumaric acid to four molecules of 3- (2 - {[4-4-trifluoromethoxy) phenyl] amino} -1 - [( 1R, 5R) -3,3,5-trimethylcyclohexyl] -1H-benzimidazol-5-yl) propanoic. Said adduct in its crystalline form has maximum peaks in an X-ray diffractogram (2 theta) such as 5.4; 6.8; 10.2; 10.3; 10.8; 11.1; 16.8 and 21.6. The present invention is useful for the treatment and prophylaxis of tumors. |
| priorityDate | 2015-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 33.